IsoEnergy Launches Comprehensive 2025 U.S. Uranium Exploration Program

• IsoEnergy has commenced a 15,000-foot drilling program at its Flatiron project in Utah's Henry Mountains district, marking the first follow-up to historic 1980s exploration work by Plateau Resources.
• The Flatiron project encompasses 8,800 acres and represents one of the largest contiguous land positions in the historically productive Henry Mountain District, where approximately 1.4 million pounds of U3O8 has been produced.
• The company will target the Salt Wash Member of the Morrison Formation, the primary uranium host unit across the Henry Mountain district, with low-grade vanadium also expected.
• IsoEnergy continues advancing its diversified uranium portfolio spanning Canada, the U.S., and Australia, with the Larocque East project in Canada's Athabasca basin featuring the world's highest-grade indicated uranium mineral resource.
• The exploration program positions IsoEnergy to capitalize on increasing demand for secure domestic uranium supply, particularly as discussions expand around the U.S. Strategic Uranium Reserve.

IsoEnergy Ltd. (NYSE American: ISOU; TSX: ISO) operates as a leading, globally diversified uranium company with substantial current and historical mineral resources across top uranium mining jurisdictions in Canada, the United States, and Australia. The company maintains assets at varying development stages, providing near-, medium-, and long-term exposure to rising uranium prices. IsoEnergy's flagship Larocque East project in Canada's Athabasca basin houses the Hurricane deposit, which boasts the world's highest-grade indicated uranium mineral resource. Additionally, the company holds a portfolio of permitted past-producing conventional uranium and vanadium mines in Utah, currently on standby with a toll milling arrangement in place with Energy Fuels, positioning IsoEnergy as a potential near-term uranium producer.

Flatiron Project: Unlocking Historic Potential

IsoEnergy's 2025 U.S. exploration program centers on the Flatiron project, where the company will complete ten surface rotary holes with core tails totaling 15,000 feet. Located in the Henry Mountains uranium district approximately seven miles northwest of IsoEnergy's past-producing Tony M uranium mine, the Flatiron project represents a significant strategic opportunity.

The company staked 370 lode claims comprising the Flatiron project in 2024, subsequently adding two Utah state leases to establish a total land position of 8,800 acres. This positioning creates one of the largest contiguous land packages in the historically productive Henry Mountain District, which has generated approximately 1.4 million pounds of U3O8 to date.

CEO Philip Williams emphasized the strategic importance of this initiative:

"Commencing these exploration programs in Utah marks an exciting new chapter for IsoEnergy in the United States. While advancing our past-producing mines toward production remains a top priority, our geological team has also identified compelling new exploration targets that we believe are ready to be tested."

The Flatiron project benefits from proven geological settings, strategically positioned along the projection of uranium mineralization trends from IsoEnergy's Tony M mine and Energy Fuels Inc.'s Bullfrog deposit. Plateau Resources, the original developers of these deposits, previously conducted wide-spaced, district-scale drilling to identify uranium mineralization concealed beneath surface cover. These historic holes were drilled on centers exceeding one mile, with two of the highest-priority results located within current Flatiron claims.

Geological Framework & Target Identification

The primary target for Flatiron drilling focuses on the lowest sandstone unit of the Salt Wash Member of the Morrison Formation, which serves as the primary host unit across the Henry Mountain district. This geological formation contains suitable reductant material and hydrogeologic settings conducive to uranium mineralization of commercially viable grade. The target unit also presents potential for low-grade vanadium encounters.

IsoEnergy's approach builds upon decades-old work that remained unexplored due to market conditions. Williams noted:

"This program will be the first to evaluate high-potential targets defined by historic work but never followed up on due to unfavourable market conditions."

The depressed uranium prices of the 1980s forced closure of regional mines before Plateau Resources could advance these promising targets, creating the opportunity IsoEnergy now seeks to exploit.

Expanding U.S. Portfolio: Daneros & Sage Plain

Beyond Flatiron, IsoEnergy's 2025 Utah exploration campaign encompasses continued fieldwork at the Daneros and Sage Plain properties. Both properties represent past producers currently on standby and ready for strategic restart. The company's detailed field work aims to reveal the sedimentary framework controlling local mineralization patterns.

This comprehensive approach includes mapping the extent of prospective host units and conducting numerous detailed measured sections of available outcrop. The work seeks to identify modern analogs of distributary channel systems, providing a conceptual target generation framework. This systematic geological analysis is expected to guide future exploration activities, including determination of appropriate geophysical survey techniques to locate productive units without requiring extensive surface drilling.

The methodical approach reflects IsoEnergy's strategy of building thorough geological understanding before committing to expensive drilling programs. This groundwork positions the company to make more informed exploration decisions and potentially reduce exploration costs through targeted survey techniques.

Market Positioning & Strategic Outlook

IsoEnergy's U.S. expansion occurs within a favorable market environment characterized by increasing focus on domestic uranium supply security. Williams highlighted this dynamic:

"The call for secure domestic uranium supply is only intensifying, as reflected in recent discussions about expanding the U.S. Strategic Uranium Reserve, and we believe IsoEnergy is well positioned to play a meaningful role as both a near- and long-term domestic supplier."

The company's diversified asset base provides multiple pathways for uranium production across different timeframes. The Utah properties offer near-term production potential given their past-producing status and standby condition, while projects like Larocque East provide long-term development opportunities with exceptional resource grades.

The toll milling arrangement with Energy Fuels provides operational flexibility for the Utah assets, eliminating the need for significant processing infrastructure investment while enabling production when market conditions warrant. This arrangement reduces capital requirements for production restart while maintaining operational control over mining activities.

Exploration Program Timeline & Execution

The 2025 exploration program represents IsoEnergy's first phase of testing at Flatiron, with drilling scheduled to commence shortly. The ten-hole, 15,000-foot program follows up on regional exploration conducted by Plateau Resources in the early 1980s, representing the first systematic evaluation of these targets in over four decades.

The program's design reflects careful consideration of historical data and geological understanding developed through previous work. By focusing on the Salt Wash Member of the Morrison Formation, IsoEnergy targets the proven host unit for uranium mineralization throughout the Henry Mountain district.

Concurrent fieldwork at Daneros and Sage Plain continues building geological framework understanding that will guide future exploration decisions. This parallel approach allows IsoEnergy to advance multiple projects simultaneously while building comprehensive geological knowledge across its Utah portfolio.

Technical Oversight & Quality Assurance

The scientific and technical information guiding IsoEnergy's exploration programs receives oversight from Dr. Dan Brisbin, P.Geo., the company's Vice President of Exploration and designated Qualified Person under NI 43-101 standards. This technical leadership ensures exploration programs meet industry standards and regulatory requirements while maintaining scientific rigor in target identification and drilling program design.

The company's technical approach builds upon established mineral resource estimates, including the Technical Report on the Tony M Project dated September 9, 2022, which provides baseline understanding of uranium mineralization in the region. This technical foundation supports informed decision-making regarding exploration target prioritization and program design.

Investment Implications & Future Outlook

IsoEnergy's 2025 U.S. exploration program positions the company to capitalize on multiple uranium market trends, including increasing focus on domestic supply security and potential expansion of strategic uranium reserves. The systematic approach to exploring historical targets that remained undeveloped due to past market conditions presents opportunities for resource discovery and expansion.

The company's diversified portfolio across multiple jurisdictions provides investors with exposure to different uranium development timelines and risk profiles. Near-term production potential from Utah assets complements long-term development opportunities from high-grade Canadian resources, creating a balanced development pipeline.

For Investors

IsoEnergy's launch of its 2025 U.S. exploration program represents a strategic expansion of the company's uranium development portfolio, targeting historically identified but unexplored mineralization in Utah's proven Henry Mountain district. The 15,000-foot drilling program at Flatiron, combined with continued geological work at Daneros and Sage Plain, positions IsoEnergy to unlock additional uranium resources in a jurisdiction increasingly focused on domestic supply security. With a diversified asset base spanning multiple countries and development timelines, IsoEnergy offers investors leveraged exposure to uranium price appreciation while maintaining multiple pathways to production across near-, medium-, and long-term horizons. The company's systematic approach to exploration, combined with existing past-producing assets ready for restart, creates a balanced portfolio suitable for investors seeking exposure to the evolving uranium sector.